Detalhe da pesquisa
1.
Assembly and Function of Heterotypic Ubiquitin Chains in Cell-Cycle and Protein Quality Control.
Cell
; 171(4): 918-933.e20, 2017 Nov 02.
Artigo
em Inglês
| MEDLINE | ID: mdl-29033132
2.
m1A in CAG repeat RNA binds to TDP-43 and induces neurodegeneration.
Nature
; 623(7987): 580-587, 2023 Nov.
Artigo
em Inglês
| MEDLINE | ID: mdl-37938769
3.
The mouse cortico-basal ganglia-thalamic network.
Nature
; 598(7879): 188-194, 2021 10.
Artigo
em Inglês
| MEDLINE | ID: mdl-34616074
4.
Publisher Correction: m1A in CAG repeat RNA binds to TDP-43 and induces neurodegeneration.
Nature
; 625(7995): E16, 2024 Jan.
Artigo
em Inglês
| MEDLINE | ID: mdl-38168622
5.
Di-valent siRNA-mediated silencing of MSH3 blocks somatic repeat expansion in mouse models of Huntington's disease.
Mol Ther
; 31(6): 1661-1674, 2023 06 07.
Artigo
em Inglês
| MEDLINE | ID: mdl-37177784
6.
PIAS1 modulates striatal transcription, DNA damage repair, and SUMOylation with relevance to Huntington's disease.
Proc Natl Acad Sci U S A
; 118(4)2021 01 26.
Artigo
em Inglês
| MEDLINE | ID: mdl-33468657
7.
Dosage sensitivity intolerance of VIPR2 microduplication is disease causative to manifest schizophrenia-like phenotypes in a novel BAC transgenic mouse model.
Mol Psychiatry
; 24(12): 1884-1901, 2019 12.
Artigo
em Inglês
| MEDLINE | ID: mdl-31444475
8.
A novel humanized mouse model of Huntington disease for preclinical development of therapeutics targeting mutant huntingtin alleles.
Hum Mol Genet
; 26(6): 1115-1132, 2017 03 15.
Artigo
em Inglês
| MEDLINE | ID: mdl-28104789
9.
Di-valent siRNA-mediated silencing of MSH3 blocks somatic repeat expansion in mouse models of Huntington's disease.
Mol Ther
; 31(11): 3355-3356, 2023 Nov 01.
Artigo
em Inglês
| MEDLINE | ID: mdl-37751745
10.
Enhanced mitochondrial biogenesis ameliorates disease phenotype in a full-length mouse model of Huntington's disease.
Hum Mol Genet
; 25(11): 2269-2282, 2016 06 01.
Artigo
em Inglês
| MEDLINE | ID: mdl-27008868
11.
P2X4 Receptor Reporter Mice: Sparse Brain Expression and Feeding-Related Presynaptic Facilitation in the Arcuate Nucleus.
J Neurosci
; 36(34): 8902-20, 2016 08 24.
Artigo
em Inglês
| MEDLINE | ID: mdl-27559172
12.
Cortical efferents lacking mutant huntingtin improve striatal neuronal activity and behavior in a conditional mouse model of Huntington's disease.
J Neurosci
; 35(10): 4440-51, 2015 Mar 11.
Artigo
em Inglês
| MEDLINE | ID: mdl-25762686
13.
A fully humanized transgenic mouse model of Huntington disease.
Hum Mol Genet
; 22(1): 18-34, 2013 Jan 01.
Artigo
em Inglês
| MEDLINE | ID: mdl-23001568
14.
Gossamer: Scaling Image Processing and Reconstruction to Whole Brains.
bioRxiv
; 2024 Apr 09.
Artigo
em Inglês
| MEDLINE | ID: mdl-38645196
15.
A novel BACHD transgenic rat exhibits characteristic neuropathological features of Huntington disease.
J Neurosci
; 32(44): 15426-38, 2012 Oct 31.
Artigo
em Inglês
| MEDLINE | ID: mdl-23115180
16.
Caspase-6 activity in a BACHD mouse modulates steady-state levels of mutant huntingtin protein but is not necessary for production of a 586 amino acid proteolytic fragment.
J Neurosci
; 32(22): 7454-65, 2012 May 30.
Artigo
em Inglês
| MEDLINE | ID: mdl-22649225
17.
Identifying polyglutamine protein species in situ that best predict neurodegeneration.
Nat Chem Biol
; 7(12): 925-34, 2011 Oct 30.
Artigo
em Inglês
| MEDLINE | ID: mdl-22037470
18.
BAC Transgenic Expression of Human TREM2-R47H Remodels Amyloid Plaques but Unable to Reprogram Plaque-associated Microglial Reactivity in 5xFAD Mice.
bioRxiv
; 2023 Aug 05.
Artigo
em Inglês
| MEDLINE | ID: mdl-37577582
19.
Microglia and complement mediate early corticostriatal synapse loss and cognitive dysfunction in Huntington's disease.
Nat Med
; 29(11): 2866-2884, 2023 Nov.
Artigo
em Inglês
| MEDLINE | ID: mdl-37814059
20.
Differential electrophysiological changes in striatal output neurons in Huntington's disease.
J Neurosci
; 31(4): 1170-82, 2011 Jan 26.
Artigo
em Inglês
| MEDLINE | ID: mdl-21273402